Justin B Schaal Selected Research

rhesus-theta-defensin-1

1/2022	Preclinical Pharmacokinetics and Safety of Intravenous RTD-1.
12/2019	RTD-1 therapeutically normalizes synovial gene signatures in rat autoimmune arthritis and suppresses proinflammatory mediators in RA synovial fibroblasts.
11/2019	Rhesus Theta Defensin 1 Promotes Long Term Survival in Systemic Candidiasis by Host Directed Mechanisms.
1/2018	Rhesus θ-Defensin-1 Attenuates Endotoxin-induced Acute Lung Injury by Inhibiting Proinflammatory Cytokines and Neutrophil Recruitment.
1/2017	Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.
1/2017	Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Justin B Schaal Research Topics

Disease

3	Infections 12/2021 - 01/2017
3	Sepsis (Septicemia) 12/2021 - 01/2012
3	Inflammation (Inflammations) 01/2018 - 01/2017
2	Acute Lung Injury 01/2022 - 01/2018
2	Arthritis (Polyarthritis) 12/2019 - 01/2017
2	Rheumatoid Arthritis 12/2019 - 01/2017
1	Severe Acute Respiratory Syndrome 01/2022
1	COVID-19 01/2022
1	Septic Shock (Toxic Shock Syndrome) 12/2021
1	Gram-Negative Bacterial Infections 12/2021
1	Candidiasis (Moniliasis) 11/2019
1	Systemic candidiasis 11/2019
1	Pulmonary Edema 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Lung Injury 01/2018
1	Joint Diseases (Joint Disease) 01/2017
1	Lung Diseases (Lung Disease) 01/2017
1	Virus Diseases (Viral Diseases) 12/2015
1	Peritonitis 01/2012

Drug/Important Bio-Agent (IBA)

6	rhesus-theta-defensin-1IBA 01/2022 - 01/2017
4	Peptides (Polypeptides)IBA 12/2021 - 12/2015
4	CytokinesIBA 12/2021 - 01/2012
3	theta-defensinIBA 12/2021 - 01/2012
3	DefensinsIBA 11/2019 - 01/2017
2	EndotoxinsIBA 01/2022 - 01/2018
2	pristane (pristan)IBA 12/2019 - 01/2017
1	Carbapenems (Carbapenem Antibiotics)IBA 12/2021
1	Antimicrobial Cationic PeptidesIBA 12/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	ChemokinesIBA 01/2018
1	Anti-Infective Agents (Microbicides)IBA 12/2015

Therapy/Procedure

1	Punctures 01/2012
1	Ligation 01/2012